Scientific evidence

Scientific publications on
DAO deficiency and its associated pathologies

Serum levels of histamine and diamine oxidase in multiple sclerosis Download pdf   Am J Clin Exp Immunol 2018;7(6):100-105 www.ajcei.us /ISSN:2164-7712/AJCEI0086352 …

Histamine intolerance (pseudoallergy) is a poorly investigated type of food hypersensitivity. The main enzyme responsible for histamine degradation in the extracellular matrix is diamine oxidase (DAO). Disturbances in the concentration or activity of DAO may lead to the development of clinical signs of allergy.

Oligomannosidic glycans at Asn-110 are essential for secretion of human diamine oxidase. download pdf   J Biol Chem. 2018 Jan 19;293(3):1070-1087. …

A Popular myth – low-histamine diet improves chronic spontaneous urticaria – fact or fiction? download pdf J Eur Acad Dermatol …

Migraine: A disorder of metabolism?   Med Hypotheses. 2016 Dec;97:117-130. doi: 10.1016/j.mehy.2016.10.029. Epub 2016 Nov 2. Kokavec A1. Author information 1 …

Characterization of recombinant human diamine oxidase (rhDAO) produced in Chinese Hamster Ovary (CHO) cells. download pdf   J Biotechnol. 2016 Jun …

Objective evaluation of intestinal mucosal damage due to anticancer drugs is generally difficult. Serum diamine oxidase (DAO) activity is reported to reflect the integrity and maturity of the small intestinal mucosa. Therefore, we investigated whether serum DAO activity is an indicator of gastrointestinal toxicity or nutritional status in patients receiving chemotherapy.